Last updated on 16th Oct 2021 - By Dwayne Michaels

How Abnormal CREATININE affects heart?

The heart’s job is to send a continuous supply of oxygenated blood around the body. The kidney filters the blood, extracting waste in the form of urine, and also helps regulate the water and salt levels to control blood pressure. New researchs have shown that heart failure is a significant risk factor for kidney disease.

Serum creatinine (a blood measurement) is an important indicator of kidney health. The kidneys are two reddish-brown bean-shaped organs found in vertebrates. Creatinine is removed from the blood chiefly by the kidneys.

If the filtration in the kidney is deficient, blood creatinine concentrations rise. Therefore, creatinine concentrations in blood and urine may be used to calculate the creatinine clearance.

In the United States and in most European countries creatinine is usually reported in mg/dL, whereas in Canada, Australia, and a few European countries, μmol/L is the usual unit. One mg/dL of creatinine is 88.4 μmol/L.

A creatinine test is most often prescribed when your active symptoms or overall health history reflect an elevated risk of kidney problems.

A decreased renal function can be caused by many types of kidney disease. Upon presentation of decreased renal function, it is recommended to perform a history and physical examination, as well as performing a renal ultrasound and a urinalysis. The most relevant items in the history are medications, edema, nocturia, gross hematuria, family history of kidney disease, diabetes and polyuria.

The kidney function can also be assessed with medical imaging. Some forms of imaging, such as kidney ultrasound or CT scans, may assess kidney function by indicating chronic disease that can impact function, by showing a small or shrivelled kidney.

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Dialysis is a treatment that substitutes for the function of normal kidneys. Dialysis may be instituted when approximately 85%-90% of kidney function is lost, as indicated by a glomerular filtration rate (GFR) of less than 15. Dialysis removes metabolic waste products as well as excess water and sodium (thereby contributing to regulating blood pressure); and maintains many chemical levels within the body.

Dialysis is typically administered three times a week for several hours at free-standing dialysis centers, allowing recipients to lead an otherwise essentially normal life.

Many renal diseases are diagnosed on the basis of a detailed medical history, and physical examination. The medical history takes into account present and past symptoms, especially those of kidney disease; recent infections; exposure to substances toxic to the kidney; and family history of kidney disease.

Kidney function is tested by using blood tests and urine tests. The most common blood test are creatinine, urea and electrolytes. Urine tests such as urinalysis can evaluate for pH, protein, glucose, and the presence of blood.