What causes high TIBC and low Transferrin saturation?

high TIBC

High TIBC and low Transferrin saturation can be caused by many reasons.

If your TIBC is in between 250 mcg/dL and 450 mcg/dL and your Transferrin saturation is in between 13 % and 45 % then you need not worry as these are the normal ranges for TIBC and Transferrin saturation respectively. But if your levels are lesser or greater than the above values, then there may be some problem in your body.

Important - Go to the end of this article and read how our patients treated their TIBC levels 

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Normal range of TIBC : 250 - 450 mcg/dL

Ideal values of TIBC depending on age :
Age Ideal TIBC value
<5 years 254.433
5-10 years 258.944
10-15 years 263.535
15-20 years 268.207
20-25 years 272.962
25-30 years 277.802
30-35 years 282.727
35-40 years 287.74
40-45 years 292.842
45-50 years 298.034
50-55 years 303.318
55-60 years 308.696
60-70 years 314.169
70-80 years 319.739
80-90 years 325.408
90-100 years 331.177
>100 years 337.049

*Ideal values are calculated based on our database of patient records

If you want your blood test report to be interpreted by TIBC specialist, then you can upload your report. Our TIBC expert will provide you with the most accurate interpretation of your blood test results and treatment within 12 hours. Upload blood test report now

1,37,160

Total number of patients treated

TIBC treatment - Click to read 10 GOLDEN ARTICLES on Anemia

Some examples of conditions that increase or decrease TIBC levels include:

  • Iron deficiency
  • Iron poisoning
  • Inflammation
  • Chronic liver disease
  • Hemochromatosis

If you want your blood test report to be interpreted by TIBC specialist, you can upload your report. Our TIBC expert will provide you with the most accurate interpretation of your blood test results and treatment within 12 hours. Upload blood test report now

Normal range of Transferrin saturation : 13 - 45 %

Ideal values of Transferrin saturation depending on age :
Age Ideal Transferrin saturation value
<5 years 13.23
5-10 years 13.465
10-15 years 13.704
15-20 years 13.947
20-25 years 14.194
25-30 years 14.446
30-35 years 14.702
35-40 years 14.963
40-45 years 15.228
45-50 years 15.498
50-55 years 15.773
55-60 years 16.053
60-70 years 16.338
70-80 years 16.628
80-90 years 16.923
90-100 years 17.223
>100 years 17.528

High TIBC and low Transferrin saturation can be caused by a lot of reasons. If you take TIBC and Transferrin saturation blood tests and the results are higher than 450 mcg/dL for TIBC and lower than 13 % for Transferrin saturation, your physician may recommend more tests to figure out the problem. You might also get these tests if your physician thinks you have some other disease.

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How the TIBC and Transferrin saturation Tests Are Done :

If your doctor wants TIBC and Transferrin saturation tests on you, you may need to go through these tests. During the TIBC and Transferrin saturation blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. Within a few hours you will get your TIBC and Transferrin saturation Test reports by your pathologist.

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Dr. Dwayne Michaels
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Dr. Dwayne Michaels
Guest Author
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